Chakraborty Ranjan

Chakraborty Ranjan
Associate Professor
Chair, Health Sciences
Significant roles: Teaching, Research & Administration
Phone: (423) 439-5853
Email:
Office Location: 249 C Lamb Hall
Mailing: Box 70673
             Johnson City, TN 37614

Dr. Ranjan Chakraborty


Education

B.S., 1979, Gujarat University, India;
M.S., 1981, University of Baroda, India;
Ph.D., 1993, Sardar Patel University, India.


Courses Taught

Intro to Microbiology
Intro to Biochemistry
Bacterial Physiology
Biotechnology


Research Focus

Bacterial Iron transport Systems

  • Molecular mechanism of Siderophore mediated iron transport in gram negative bacteria
  • Novel siderophores from Rhizobia
  • Siderophore mediated iron transport in community and clinical isolates of Methicillin resistant Staphylococcus aureus (MRSA).

Selected Publications

1. Patel, H. N., Chakraborty, R. N. and Desai, S. B. (1994) Effect of Iron on Siderophore Production and Outer membrane Proteins of Rhizobium leguminosarum IARI102. Current Microbiology, (NY, USA), 28, 119.

2. Chakraborty, R. N., Patel, H. N. and Desai, S. B. (1994) Studies on Iron Uptake and Its Effect on the Outer membrane Proteins of Pseudomonas stutzeri RC7, Current Microbiology, (NY, USA), 28, 321.

3. Susan K. Buchanan, Barbara S. Smith, Lalitha Venkatramani, Di Xia, Lothar Esser, Maya Palnitkar, Ranjan Chakraborty, Dick van der Helm, Johann Deisenhofer. (1999), Crystal Structure of the Outer membrane Active Transporter FepA from Escherichia coli. Nature (Structural Biology), 6(1), 56.

4. Dick van der Helm and Chakraborty, R. N. (2001): ?Structures of Siderophore Receptors?., Ed: Winkelmann, G. : Microbial Transport Systems. Wiley-VCH Verleg GmbH, Weinheim, Germany., pp. 261-288.

5. Ferguson Andrew, Chakraborty R.N., Barbara Smith, Lothar Essar, Dick van der Helm and Johann Deisenhofer (2002) Structural basis of gating by the outer membrane transporter FecA. Science, 295, 1715-1719.

6. van der Helm D., Chakraborty, R., Ferguson A.D., Smith, B. S., Esser, L., and Deisenhofer, J. (2002) Bipartite gating in the outer membrane protein FecA. Biochem. Soc. Trans., 30, 708-710.

7. Chakraborty, R. N., Edward Lemke, Cao, Z., Klebba, P. E. and Dick van der Helm. (2003) Identification and Mutational Studies of Conserved Amino acids in the outer membrane receptor protein FepA, which affect Transport but not Binding of Ferric Enterobactin in Escherichia coli. BioMetals, 16, 507-518.

8. Storey, E.P., Little, J., Lowman, D., and R. Chakraborty (2006) Characterization of ?Schizokinen?; a dihydroxamate siderophore produced by Rhizobium leguminosarum IARI 917. BioMetals, 19, 637-649.

9. Chakraborty, R., Storey, E.P., and Dick van der Helm (2007) Molecular mechanism of ferricsiderophore passage through the outer membrane receptor proteins of Escherichia coli. BioMetals, 20, 263-274.

10. Lopez, Claudia, Alice, A. F., Chakraborty, R. and J. H. Crosa (2007) Identification of amino acid residues         required for ferric-anguibactin transport in the outer membrane receptor FatA of V. anguillarum. Microbiology, 153, 570-584.


Personal Interests

Music (Indian classical and semi classical, Western Jazz, Pop and Country) and Painting