Clara Pearson McClure, MSEH
Research Specialist, Department of Environmental and Occupational Health and Safety
Sciences
EDUCATION
East Tennessee State University
M.S.E.H. (Master of Science in Environmental Health), December 2013
University of Tennessee
B.A. in Psychology, May 2009
PROFESSIONAL EXPERIENCE
Adjunct Professor
East Tennessee State University
Taught Water Supplies and Wastewater Treatment, Toxicology, and Environmental Health Practice
Fall 2022, Spring 2023, Fall 2023
Earth School Instructor
Fauna Forest Farm, Jonesborough, TN
Instructor for children ages 3-6
February-December 2023
Research Assistant
ETSU Quillen College of Medicine, Department of Internal Medicine
June 2013-September 2015
Graduate Assistant
ETSU Environmental Health Sciences Laboratory
August 2010-May 2013
Laboratory Instructor
ETSU Department of Environmental Health
Taught Environmental Analysis and Bio-Analysis
Spring 2011, Fall 2012
LABORATORY TECHNIQUES
Laboratory Techniques: Flow Cytometry, magnetic assisted cell sorting, RNA and DNA extraction, PCR, Protein Isolation/Fractionation, Western and Northern blots, enzyme-linked immunosorbent assays, cell culture and stimulation, cell transfection by electroporation, small animal surgery, isolation of bone marrow cells from mice, isolation of peripheral blood mononuclear cells from human blood, operation of Agilent Gas Chromatographer, Organic Carbon Analyzer, Spectrophotometer; Management of team sampling events; Water quality analyses including alkalinity, ammonia, bioaerosols assessment, biochemical oxygen demand, hardness, nitrates, phosphates, sulfates, total organic carbon, total suspended solids, total/fecal Coliforms; Sediment analysis including microbial enzyme activities; Standard plate counts and microscopic plate counts.
RESEARCH INTERESTS
Environmental Justice, Water Quality, Air Quality, Food Quality
PUBLICATIONS
Master’s Thesis: Long-term Recovery of South Indian Creek Following Interstate Construction
McClure, C, Brudecki, L, Yao, ZQ, McCall CE, El Gazzar, M. Processing Body Formation Limits Proinflammatory Cytokine Synthesis in Endotoxin-Tolerant Monocytes and Murine Septic Macrophages. Journal of Innate Immunity, May 2015.
McClure, C, Brudecki, L, Ferguson, DA, Yao, ZQ, Moorman, JP, McCall, CE, El Gazzar, M. MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis. Infection and Immunity, September 2014, vol. 82, 3816-3825.
McClure, C, Ali, E, Youssef, D, Yao, ZQ, McCall CE, El Gazzar, M. NFI-A disrupts myeloid cell differentiation and maturation in septic mice. Journal of Leukocyte Biology, August 2015.
PRESENTATIONS
Michael Davis, B.Sc., Clara McClure, M.Sc., Mohamed El Gazzar, Ph.D. Mitogen-activated protein kinase phosphatase 1 disrupts proinflammatory protein synthesis in endotoxin-adapted monocytes. Presented at the ETSU Boland Research Forum, April 2014.
Liberty Foye, Clara McClure, MS, Mohamed El Gazzar, PhD. P-body formation limits proinflammatory cytokine synthesis in endotoxin tolerant monocyte and septic macrophages. Presented at the ETSU Appalachian Research Forum, April 2015.
Ekram Ali, Clara McClure, MS, Mohamed El Gazzar, PhD. NFI-A disrupts innate immunity cell differentiation and maturation in sepsis. Presented at the ETSU Appalachian Research Forum, April 2015.
SERVICE ACTIVITIES
Public Health Student Association Member
Tennessee Environmental Health Association Member
Appalachian Service Project Volunteer
One Acre Café Volunteer
Coalition for Kids Volunteer
PERSONAL INTERESTS
Being out in nature
Hiking with my son and dog
Spending time with friends and family
Painting
Writing